Evidence for Neuromodulation

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Madore, Michelle R. et al. 

In this research study, repetitive transcranial magnetic stimulation (TMS) was evaluated as a treatment for veterans with pharma-resistant major depressive disorder (MDD), with many also experiencing post-traumatic stress disorder (PTSD). The study included 770 veterans who received TMS sessions, many showing significant and meaningful reductions in both MDD and PTSD symptoms.

Clark, Caroline et al. 

In this research study, TMS was explored as a non-invasive treatment option for patients with PTSD who have not found sufficient relief through conventional therapies like psychotherapy, medication, or complementary treatments. While the ideal TMS settings and specific brain targets vary, the study suggests that it could be a valuable addition to PTSD treatment programs.

Guo, Bingqui et al. 

In this research study, the relationship between neuroinflammation and mood disorders such as anxiety and depression is explored. The review highlights findings that therapies like TMS and deep brain stimulation (DBS) have been shown to decrease pro-inflammatory factors in the brain, which may contribute to symptom relief. 

Val-Laillet, D. et al. 

In this research study, brain imaging and neuromodulation techniques are examined to understand and potentially treat obesity and eating disorders, such as binge eating and anorexia nervosa. Neuroimaging reveals anomalies in the prefrontal cortex and reward pathways in individuals with disordered eating. Non-invasive neuromodulation methods, such as repetitive transcranial magnetic stimulation (rTMS), and transcranial direct-current stimulation (tDCS), show promise in altering these brain responses to improve eating behavior.